The 24 sides through from the group phase join the eight third-placed finishers in the Champions League in Monday's draw, including Manchester United and Ajax Amsterdam.
IMAGES from the Premier League matches played on Saturday
Chelsea manager Carlo Ancelotti has told arch rivals Arsenal that its time to show their mettle for the Premier League title.
Manchester United, winners of the competition in 2017, will have a lot of travelling to do to Eastern Europe after being drawn alongside Kazakhstan side Astana, Serbia's Partizan Belgrade and Dutch side AZ Alkmaar.
Newcastle United's clash with AFC Wimbledon was postponed after flooding damaged the Wimbledon pitch on Monday.
The unusual circumstances forced by the COVID-19 pandemic will level the playing field, says Arsenal manager Mikel Arteta
'We changed our attitude, desire and organisation at halftime and then we were completely different. It was good for my players to learn and to suffer on the pitch'
Roberto Firmino's 90th-minute header sent Liverpool back to the top of the Premier League with a 2-1 victory over Tottenham Hotspur, whose 11-match unbeaten run came to an end on Wednesday.
Arsenal substitute Pierre-Emerick Aubameyang scored twice in three minutes and captain Mesut Ozil played a starring role as they extended their winning run with a 3-1 victory over Leicester City in the Premier League on Monday.
The defeat halted Brighton's impressive three-game winning streak which included a 4-1 win over Chelsea and a 3-1 victory at Arsenal in the League Cup on Wednesday.
Left-back Saka and striker Eddie Nketiah netted inside 26 minutes as Arsenal's much-changed lineup made a dominant start
Leicester keeper Schmeichel defends under-fire De Gea
Arsenal's fans had waited nine long months to return to the club's north London stadium but the 2,000 people sprinkled across the red seats had to wait only nine minutes to enjoy the thrill of celebrating a goal in the flesh again on Thursday.
The draw also produced a clash between two former European champions with AC Milan facing Serbia's Red Star Belgrade while French league leaders Lille face Ajax Amsterdam in a fascinating tie.
Images from Saturday's third round matches in the FA Cup.
A round-up of Sunday night's matches in the Premier League.
Arsene Wenger acknowledged Southampton were the sharper team as they crushed Arsenal 4-0 on Saturday but he also blamed the defeat on bad luck.
Steven Bergwijn scored twice in stoppage time as Tottenham Hotspur stunned Leicester City and pulled off a remarkable 3-2 victory in the Premier League on Wednesday.
IMAGES from the English Premier League matches played on Sunday.
Aston Villa returned to winning ways in stunning fashion as Ollie Watkins scored twice in a 3-0 away thumping of an abject Arsenal in drizzly north London on Sunday.
Liverpool's slim Premier League title hopes faded further on Saturday when Michail Antonio's late header earned West Ham United a deserved point with a 2-2 draw.
Third-placed Aston Villa are the surprise package of the season and Unai Emery's side face relegation-threatened Burnley while fifth-placed Spurs host a resurgent Bournemouth who have 19 points from their last seven games.
Lacazette fired the Gunners ahead in the eighth minute after poor defending by the home side before new signing Gabriel made it 2-0 in the 49th and Aubameyang put the icing on the cake with a superb shot into the top corner.
Manchester City withdrew from the battle to secure the services of Arsenal's Chilean forward Alexis Sanchez, leaving Jose Mourinho's Manchester United as the most likely destination for the 29-year-old.
Cristiano Ronaldo came off the bench to earn Manchester United a hard-fought 2-1 victory at Everton in the Premier League on Sunday, taking his career goal tally to 700 in the process.
;You will have setbacks. We beat Arsenal, we beat Liverpool. On Sunday, we had a bad day at the office. City were better, we have to accept that. But we can't accept our unacceptable performance. So thank you for the lesson, Pep and City. We have to understand, we have to do things much better.'
Imperious Liverpool extended their Premier League home winning streak against Arsenal to six on Saturday with an easy 4-0 victory that lifted them to second in the table.
Images from the English Premier League matches played on Saturday.
The Indian Army is enhancing the combat prowess of its artillery units along the frontier with China by procuring an array of weapons systems, including an additional batch of 100 K9 Vajra howitzers, swarm drones, loitering munitions and surveillance systems.
Arsenal's young guns continued to shine as they dismantled Standard Liege 4-0 on a hectic night of Europa League action that produced a full house of Spanish victories on Thursday. A summary of the matches.
Images from the English Premier League matches played on Saturday.
Antonio Valencia's early thunderbolt put Manchester United en route to a 4-0 Premier League victory over Everton on Sunday, but they needed a flurry of late goals to finally subdue their unfortunate visitors.
Arsenal finished eighth in the Premier League but their record 14th FA Cup triumph last Saturday ensured another year of European football and the possibility of earning up to 40 million pounds ($52.58 million) in the Europa League.
Sancho, who has played 58 league games since joining United in 2021, said he respects all decisions made by the coaching staff.
Champions Liverpool are five points clear at the top of the Premier League after a 7-0 away hammering of Crystal Palace while Arsenal's troubles continued with a 2-1 defeat at second-placed Everton on Saturday.
Bolton Wanderers squandered a chance to leap into the Champions League places when they were held 1-1 at home by Everton while fourth-placed Arsenal drew 0-0 at Newcastle United in the Premier League on Monday.
Ronaldo's 62nd minute strike was his 17th league goal this season
IMAGES from soccer matches played in the EPL, La Liga and Serie A on Tuesday.
IMAGES from Europa League matches played on Thursday.
Images from Sunday's action in the Premier League.